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  2. Stability testing (pharmaceutical) - Wikipedia

    en.wikipedia.org/wiki/Stability_testing...

    With stability testing, pharmaceutical industry inspects the quality of drug substances and drug products as per the guidelines outlined by US Food and Drug Administration and International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use to make sure that they retained the quality over the period of time.

  3. Shelf Life Extension Program - Wikipedia

    en.wikipedia.org/wiki/Shelf_Life_Extension_Program

    One exception occurred during the 2010 Swine Flu Epidemic when the FDA authorized expired Tamiflu based on SLEP Data. [9]The US FDA is able to extend the shelf life of drugs throughout national, state, local, tribal, and territorial stockpiles through two legal means: by issuing an Emergency Use Authorization on using a drug past its expiration date (which is legally an unapproved use of a ...

  4. Investigational New Drug - Wikipedia

    en.wikipedia.org/wiki/Investigational_new_drug

    Preclinical testing consists of animal pharmacology and toxicology studies to assess whether the drug is safe for testing in humans. Also included are any previous experience with the drug in humans (often foreign use). Manufacturing Information includes composition, manufacturer, and stability of, and the controls used for, manufacturing the ...

  5. Pharmaceutical formulation - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_formulation

    A knowledge of stability is essential by this stage, and conditions must have been developed to ensure that the drug is stable in the preparation. If the drug proves unstable, it will invalidate the results from clinical trials since it would be impossible to know what the administered dose actually was.

  6. DrugBank - Wikipedia

    en.wikipedia.org/wiki/DrugBank

    Version 3.0 also included drug transporter data, drug pathway data, drug pricing, patent and manufacturing data as well as data on >5000 experimental drugs. Version 4.0 was released in 2014. [ 4 ] This version included 1558 FDA-approved small molecule drugs, 155 biotech drugs and 4200 unique drug targets.

  7. System to Retrieve Information from Drug Evidence - Wikipedia

    en.wikipedia.org/wiki/System_to_Retrieve...

    The System to Retrieve Information from Drug Evidence (STRIDE) is a United States Drug Enforcement Administration (DEA) program consisting of six subsystems providing information on drug intelligence, statistics on markings found on pills and capsules, drug inventory, tracking, statistical information on drugs removed from the marketplace, utilization of laboratory manpower and information on ...

  8. KEGG - Wikipedia

    en.wikipedia.org/wiki/KEGG

    KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.KEGG is utilized for bioinformatics research and education, including data analysis in genomics, metagenomics, metabolomics and other omics studies, modeling and simulation in systems biology, and translational research in drug development.

  9. Drug Master File - Wikipedia

    en.wikipedia.org/wiki/Drug_Master_File

    In the United States, DMFs are submitted to the Food and Drug Administration (FDA). The Main Objective of the DMF is to support regulatory requirements and to prove the quality, safety and efficacy of the medicinal product for obtaining an Investigational New Drug Application (IND), a New Drug Application (NDA),As an Abbreviated New Drug Application (ANDA), another DMF, or an Export Application.