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A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages. [3] Testicular seminoma originates in the germinal epithelium of the seminiferous ...
Spermatocytic tumor is a rare tumour, making up only one to two percent of all testicular germ cell tumours. Men presenting with this tumour are generally 50 to 60 years old, and its occurrence is rare in men under 30 years old. Most present with slow, painless testicular enlargement, which may involve both testes. [1]
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
Germ cells tumors constitute a vast majority of the incidences of testicular tumors. [3]GCTs are classified by their histology, [4] regardless of location in the body. . However, as more information about the genetics of these tumors become available, they may be classified based on specific gene mutations that characterize specific tu
The World Health Organization classification of testicular tumours [4] subdivides ITGCN into (1) a more common, unspecified type (ITGCNU), and (2) other specific subtypes. The most common specific subtypes are intratubular embryonal carcinoma and intratubular seminoma. [citation needed]
The treatment for mediastinal nonseminomatous germ cell tumors should follow guidelines for poor-prognosis testicular cancer. Initial treatment with four courses of bleomycin, etoposide, and cisplatin, followed by surgical resection of any residual disease, is considered standard therapy.
It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation needed] A 7.4 x 5.5-cm seminoma in a radical orchiectomy specimen from a 27-year-old man . Seminoma is the second-most common testicular cancer; the most common is mixed, which may contain seminoma. [citation needed]
Fig. 3. Seminoma. (a) Seminoma usually presents as a homogeneous hypoechoic nodule confined within the tunica albuginea. (b) Sonography shows a large heterogeneous mass occupying nearly the whole testis but still confined within the tunica albuginea, it is rare for seminoma to invade to peritesticular structures. [citation needed]