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Germ cell tumor (GCT) is a neoplasm derived from the primordial germ cells. [1] Germ-cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads (ovary [2] and testis). GCTs that originate outside the gonads may be birth defects resulting from errors during development of the embryo.
M9064/2 Intratubular malignant germ cells Intratubular germ cell neoplasia; M9064/3 Germinoma Germ cell tumor, NOS; M9065/3 Germ cell tumor, nonseminomatous M9070/3 Embryonal carcinoma, NOS Embryonal adenocarcinoma; M9071/3 Yolk sac tumor. Endodermal sinus tumor; Polyvesicular vitelline tumor; Orchioblastoma; Embryonal carcinoma, infantile ...
Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.
Not all germ cell tumors (GCTs) arise from intratubular germ cell neoplasia. The following testicular GCTs do not arise from ITGCN: Spermatocytic tumor [5] Pediatric Yolk sac tumors (endodermal sinus tumour). [6] This is currently an area of controversy as some authors dispute the absence of ITGCN in these cases. [3] Teratoma (rare exceptions) [3]
Dysgerminoma is the most common type of malignant germ-cell ovarian cancer. Dysgerminoma usually occurs in adolescence and early adult life; about 5% occur in prepubertal children. Dysgerminoma is extremely rare after age 50. It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation ...
A dysgerminoma is a type of germ cell tumor; [1] it usually is malignant and usually occurs in the ovary.. A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis [2] or germinoma in the central nervous system or other parts of the body.
A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages.
These rare forms of teratoma with malignant transformation may contain elements of somatic (not germ cell) malignancy such as leukemia, carcinoma, or sarcoma. [35] A teratoma may contain elements of other germ cell tumors, in which case it is not a pure teratoma, but rather is a mixed germ cell tumor and is malignant.