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  2. Phosphoribosyl pyrophosphate - Wikipedia

    en.wikipedia.org/wiki/Phosphoribosyl_pyrophosphate

    Phosphoribosyl pyrophosphate (PRPP) is a pentose phosphate. It is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate , as well as in pyrimidine nucleotide formation.

  3. Hypoxanthine-guanine phosphoribosyltransferase - Wikipedia

    en.wikipedia.org/wiki/Hypoxanthine-guanine...

    n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene. HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. This ...

  4. Adenine phosphoribosyltransferase deficiency - Wikipedia

    en.wikipedia.org/wiki/Adenine_phosphoribosyl...

    Adenine phosphoribosyltransferase (APRT) catalyzes the creation of pyrophosphate and adenosine monophosphate from 5-phosphoribosyl-1-pyrophosphate and adenine. Adenine phosphoribosyltransferase is a purine salvage enzyme. Genetic mutations of adenine phosphoribosyltransferase make large amounts of 2,8-Dihydroxyadenine causing urolithiasis and ...

  5. PRPSAP1 - Wikipedia

    en.wikipedia.org/wiki/PRPSAP1

    Phosphoribosyl pyrophosphate synthetase-associated protein 1 is an enzyme that in humans is encoded by the PRPSAP1 gene. [5] [6] References

  6. PRPSAP2 - Wikipedia

    en.wikipedia.org/wiki/PRPSAP2

    The enzyme phosphoribosyl pyrophosphate synthetase (PRS) catalyzes the formation of phosphoribosyl pyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits.

  7. Urine electrolyte levels - Wikipedia

    en.wikipedia.org/wiki/Urine_electrolyte_levels

    If potassium is being lost through the kidneys, urine potassium will likely be high. If urine potassium is low, this suggests a non-renal cause. [7] Urinary calcium (Ca) – per day: 2.5: 6.25: mmol / 24 h: An abnormally high level is called hypercalciuria and an abnormally low rate is called hypocalciuria. 14637-3: 100 [8] 250 [8] mg / 24 ...

  8. Orotate phosphoribosyltransferase - Wikipedia

    en.wikipedia.org/wiki/Orotate_phosphoribosyl...

    When orotate is present, pyrophosphate binding affinity is increased fourfold and the reaction undergoes burst kinetics, with rapid phosphoribosyl transfer and then slow release of products. [7] This slow release is thought to be due to the solvent-exposed loop of orotate phosphoribosyltransferase that protects the active site during the first ...

  9. Urinalysis - Wikipedia

    en.wikipedia.org/wiki/Urinalysis

    It normally ranges from 1.003 to 1.035; lower values indicate that the urine is dilute, while higher values mean that it is concentrated. A urine specific gravity that consistently remains around 1.010 (isosthenuria) can indicate kidney damage, as it suggests that the kidneys have lost the ability to control urine concentration. [39]