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Many diseases cause sweat gland dysfunction: Acromegaly, a result of excess growth hormone, causes the size of sweat glands increase, which leads to thicker skin. [71] Aquagenic wrinkling of the palms, in which white papules develop on the palms after exposure to water, can sometimes come with abnormal aquaporin 5 in the sweat glands. [72]
For palmoplantar hyperhidrosis, 20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol () is the most effective topical treatment. [4] Other topical treatments such as potassium permanganate, tannic acid (2 to 5 percent solutions), resorcinol, boric acid, formaldehyde, methenamine, and glutaraldehyde have yielded less than desirable results.
Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, [1] [2] more than is required for the regulation of body temperature. [3] Although it is primarily a physical burden, hyperhidrosis can deteriorate the quality of life of the people who are affected from a psychological, emotional, and social perspective. [4]
Focal hyperhidrosis, also known as primary hyperhidrosis, is a disease characterized by an excessive sweating localized in certain body regions (particularly palms, feet and underarms). Studies suggest that this condition, affecting between 1% and 3% of the US population, seems to have a genetic predisposition in about two thirds of those affected.
Perspiration, also known as sweat, is the fluid secreted by sweat glands in the skin of mammals. [ 1 ] Two types of sweat glands can be found in humans: eccrine glands and apocrine glands . [ 2 ]
The amount of sweat glands varies across the human body, being highest in hand and foot regions (200–600 sweat glands per cm 2). [19] The response of the skin and muscle tissue to external and internal stimuli can cause the conductance to vary by several microsiemens .
Eccrine sweat glands are found in virtually all skin, with the highest density in the palms of the hands, and soles of the feet, and on the head, but much less on the torso and the extremities. In other mammals, they are relatively sparse, being found mainly on hairless areas such as foot pads.
Apocrine sweat glands: skin: coiled tubular 2 Bauhin's glands, anterior lingual glands tongue, near tip nonserous or mixed 3 Brunner's glands, duodenum: mucous: compound tubular 4 Bronchopulmonary glands: lungs: mucous 5 Bulbourethral glands, Cowper's glands, Mery's glands penis, base pre-ejaculate: tubulo-alveolar 6 Ceruminous gland: ear ...