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The evaluation of a skin nodule includes a description of its appearance, its location, how it feels to touch and any associated symptoms which may give clues to an underlying medical condition. [4] Often discovered unintentionally on a chest x-ray, a single nodule in the lung requires assessment to exclude cancer. [9]
Nodular density is used to distinguish larger lung tumors, smaller infiltrates or masses with other accompanying characteristics. An often used formal radiological definition is the following: a single lesion in the lung completely surrounded by functional lung tissue with a diameter less than 3 cm and without associated pneumonia , atelectasis ...
Nodular basal-cell carcinoma (also known as "classic basal-cell carcinoma") accounts for 50% of all BCC. [29] It most commonly occurs on the sun-exposed areas of the head and neck. [ 30 ] : 748 [ 31 ] : 646 Histopathology shows aggregates of basaloid cells with well-defined borders, showing a peripheral palisading of cells and one or more ...
Mummified RSCs (compact nucleus, basophilic cytoplasm, no nucleolus) are also associated with classical Hodgkin's lymphoma while popcorn cells (small cell with hyper-lobulated nucleus and small nucleoli) are lymph histiocytic (L-H) variant of Reed–Sternberg cells and are associated with nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).
Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a slow-growing CD20 positive form of Hodgkin lymphoma, a cancer of the immune system's B cells. [ 1 ] [ 2 ] NLPHL is an uncommon sub-type of Hodgkin lymphoma, making up 5-10% of Hodgkin lymphomas. [ 3 ]
Enlargement of the spleen is a requirement for the diagnosis of SMZL and is seen in nearly all people affected by SMZL (often without lymphadenopathy). [1] Aside from the uniform involvement of the spleen, the bone marrow is frequently positive in patients with SMZL displaying a nodular pattern with morphology similar to what is observed in the splenic hilar lymph nodes. [7]
Nodular sclerosing Hodgkin lymphoma ("NSHL") or Nodular sclerosis is a form of Hodgkin's lymphoma [1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years.
Medical genetics An accessory spleen is a small nodule of splenic tissue found apart from the main body of the spleen . Accessory spleens are found in approximately 10 percent of the population [ 1 ] and are typically around 1 centimetre in diameter.