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Poliosis is present in half of patients with segmental vitiligo. [ 5 ] Vogt-Koyanagi-Harada Syndrome (VKH): VKH is a systemic autoimmune disorder affecting melanin-containing tissues, leading to uveitis , meningitis , and poliosis, which often involves the eyebrows and eyelashes.
The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation.
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
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This results in either the entire surface (if all pigment cells fail to develop) or patches of body surface (if only a subset are defective) having a lack of cells that can make pigment. Since all pigment cell-types differentiate from the same multipotent precursor cell-type, leucism can cause the reduction in all types of pigment.
It can also be connected to the skin's immune response. LED PUVA lamps give much more intense light compared to fluorescent type lamps. This reduces the treatment time, makes the treatment more effective, and enables the use of a weaker psoralen. The physician and physiotherapists can choose a starting dose of UV based on the patient's skin type.
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