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The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In the context of diabetes or hypoglycemia, a measurement of C-peptide blood serum levels can be used to distinguish between different conditions with similar clinical features.
The C peptide-A chain junction occurs between residues 64 and 65 of proinsulin. These are lysine and arginine molecules, respectively. [10] The C peptide-B chain connection is between two arginine residues at positions 31 and 32 of proinsulin. [10] There is conservation of much of the structure of proinsulin among mammalian species, with much ...
The C-terminal telopeptide (CTX), also known as carboxy-terminal collagen crosslinks, is the C-terminal telopeptide of fibrillar collagens such as collagen type I and type II. It is used as a biomarker in the serum to measure the rate of bone turnover .
C-peptide, which is secreted into the bloodstream in equimolar quantities to insulin. C-peptide helps to prevent neuropathy and other vascular deterioration related symptoms of diabetes mellitus. [20] A practitioner would measure the levels of C-peptide to obtain an estimate for the viable beta cell mass. [21]
C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells .
An insulin tolerance test (ITT) is a medical diagnostic procedure during which insulin is injected into a patient's vein, after which blood glucose is measured at regular intervals.
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C/C/E: clubbing, cyanosis, and edema (general signs of cardiovascular disease) CCG: Clinical commissioning group: CCF: congestive cardiac failure: CCK: cholecystokinin: CCK-PZ: cholecystokinin-pancreozymin: CCNS: cell cycle–nonspecific [drug] (a type of drug used in chemotherapy) CCOC: clear cell odontogenic carcinoma: CCOT