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The primary symptom is yellowish discoloration of the white part of the eyes and skin in a newborn baby. [1] Other symptoms may include excess sleepiness or poor feeding. [1] A bilirubin level more than 34 μmol/L (2 mg/dL) may be visible. [1] For the feet to be affected level generally must be over 255 μmol/L (15 mg/dL). [1]
The light pad is usually placed on the undressed baby's back with a diaper on. Clothing may be worn, but the clothing should be placed over the light pad, and the light pad should still be in direct contact with the baby's skin. The light pad should never be placed on the baby's head. [11] The baby can sleep, eat, or be held while the light pad ...
Neonatal cholestasis refers to elevated levels of conjugated bilirubin identified in newborn infants within the first few months of life. [1] Conjugated hyperbilirubinemia is clinically defined as >20% of total serum bilirubin or conjugated bilirubin concentration greater than 1.0 mg/dL regardless of total serum bilirubin concentration. [2]
Intact maternal detoxification protects baby during intrauterine life, yet after delivery, the baby struggles with the aflatoxin in its blood and liver. Moreover, the baby feeds aflatoxin M 1 from its mom, as aflatoxin M 1 is the detoxification product of aflatoxin B1. It is a milder toxin that causes cholangitis in the baby. [17]
The bilirubin level found in the body reflects the balance between production and excretion. Blood test results are advised to always be interpreted using the reference range provided by the laboratory that performed the test. The SI units are μmol/L. [52] Typical ranges for adults are: [53] 0–0.3 mg/dl – Direct (conjugated) bilirubin level
Kernicterus is a bilirubin-induced brain dysfunction. [1] The term was coined in 1904 by Christian Georg Schmorl.Bilirubin is a naturally occurring substance in the body of humans and many other animals, but it is neurotoxic when its concentration in the blood is too high, a condition known as hyperbilirubinemia.