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In humans, the cerebrum is the largest and best-developed of the five major divisions of the brain. The cerebrum is made up of the two cerebral hemispheres and their cerebral cortices (the outer layers of grey matter), and the underlying regions of white matter. [2] Its subcortical structures include the hippocampus, basal ganglia and olfactory ...
The cerebral cortex, also known as the cerebral mantle, [1] is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals.It is the largest site of neural integration in the central nervous system, [2] and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness.
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. The concept was first introduced by the German anatomist Korbinian Brodmann in the early 20th century.
The brainstem, resembling a stalk, attaches to and leaves the cerebrum at the start of the midbrain area. The brainstem includes the midbrain, the pons, and the medulla oblongata. Behind the brainstem is the cerebellum (Latin: little brain). [7] The cerebrum, brainstem, cerebellum, and spinal cord are covered by three membranes called meninges.
Cerebral peduncle. Crus cerebri; Mesencephalic cranial nerve nuclei. Oculomotor nucleus (III) Edinger-Westphal nucleus; Trochlear nucleus (IV) Mesencephalic duct (cerebral aqueduct, aqueduct of Sylvius)
The name cerebellum is a diminutive of cerebrum (brain); [94] it can be translated literally as little brain. The Latin name is a direct translation of the Ancient Greek παρεγκεφαλίς ( parenkephalis ), which was used in the works of Aristotle, the first known writer to describe the structure. [ 95 ]
The Purkinje layer of the cerebellum, which contains the cell bodies of the Purkinje cells and Bergmann glia, express a large number of unique genes. [9] Purkinje-specific gene markers were also proposed by comparing the transcriptome of Purkinje-deficient mice with that of wild-type mice. [10]
Defining cerebral cytoarchitecture began with the advent of histology—the science of slicing and staining brain slices for examination. [2] It is credited to the Viennese psychiatrist Theodor Meynert (1833–1892), who in 1867 noticed regional variations in the histological structure of different parts of the gray matter in the cerebral hemispheres.