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  2. Mavacamten - Wikipedia

    en.wikipedia.org/wiki/Mavacamten

    Mavacamten, sold under the brand name Camzyos, is a medication used to treat obstructive hypertrophic cardiomyopathy. [8] [9] Mavacamten is a small-molecule allosteric [10] and cardiac myosin inhibitor. [8] It was developed by MyoKardia, a subsidiary of Bristol Myers Squibb. [11]

  3. Disopyramide - Wikipedia

    en.wikipedia.org/wiki/Disopyramide

    Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, occurring in 1:500 individuals in the general population. It is estimated that there are 600,000 individuals in the United States with hypertrophic cardiomyopathy.

  4. 8 Common Cardiovascular Diseases for Men & How to Prevent Them

    www.aol.com/8-common-cardiovascular-diseases-men...

    Hypertrophic cardiomyopathy doesn’t always need treatment, but doctors often recommend weight loss and may prescribe medications such as: Beta-blockers Calcium-channel blockers

  5. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    class II-III obstructive hypertrophic cardiomyopathy: Trastuzumab deruxtecan: Daiichi Sankyo: granted for three indications: HER2-positive breast cancer with prior anti-HER2-based treatment; HER2 low (IHC 1+ or IHC 2+/ISH) breast cancer; and non-small cell-lung cancer with an activating HER2 mutation Dupilumab: Regeneron Pharmaceuticals

  6. Bristol Myers Squibb - Wikipedia

    en.wikipedia.org/wiki/Bristol_Myers_Squibb

    In October, BMS announced it would acquire cardiology company MyoKardia for $13.1 billion ($225 per share) gaining control of mavacamten, a cardiovascular drug for obstructive hypertrophic cardiomyopathy (HCM), and the development of two key treatments: danicamtiv (MYK-491) and MYK-224. [78]

  7. Hypertrophic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy

    Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles . [ 10 ]

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