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However, because radiation therapy causes tissue changes, prostatectomy after radiation has higher risks of complications. To avoid the adverse side effects of a radical prostatectomy, doctors may recommend deferred treatment which can involve observation and palliative treatment or active monitoring with some local treatments as needed.
Early radiation enteropathy is very common during or immediately after the course of radiotherapy. This involves cell death, mucosal inflammation and epithelial barrier dysfunction. This injury is termed mucositis and results in symptoms of nausea, vomiting, fatigue, diarrhea and abdominal pain. [1] [6] It recovers within a few weeks or months.
Radiation proctitis can occur a few weeks after treatment, or after several months or years: Acute radiation proctitis — symptoms occur in the first 3 months after therapy. [4] These symptoms include diarrhea and the urgent need to defecate. Radiation associated vascular ectasias (RAVE) and chronic radiation proctopathy — previously known ...
Dr. Narayanan says that bone pain can also be a sign of prostate cancer recurrence in patients who have already had the disease. The link between prostate cancer and bone pain may be a surprising one.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by pelvic or perineal pain without evidence of urinary tract infection, [8] lasting longer than 3 months, [9] as the key symptom. Symptoms may wax and wane. Pain can range from mild to debilitating. Pain may radiate to the back and rectum, making sitting uncomfortable.
Radiation colitis is injury to the colon caused by radiation therapy. It is usually associated with treatment for prostate cancer or cervical cancer . [ 1 ] Common symptoms are diarrhea , a feeling of being unable to empty the bowel , [ 2 ] gastrointestinal bleeding, and abdominal pain.