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Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with opioid use disorder (OUD). [1] In the case of methadone maintenance treatment (MMT), methadone is used to treat dependence on heroin or other opioids, and is administered on an ongoing basis.
Methadone is made by chemical synthesis and acts on opioid receptors. [7] Methadone was developed in Germany in the late 1930s by Gustav Ehrhart and Max Bockmühl. [17] [18] It was approved for use as an analgesic in the United States in 1947, and has been used in the treatment of addiction since the 1960s.
In many parts of the United States, methadone clinics are few and far between, which presents problems for addicts seeking methadone treatment who live far from a clinic. All methadone clinics must register as an accredited opioid treatment program with the Substance Abuse and Mental Health Service Administration and renew yearly or every three ...
An opioid treatment program not only prescribes and dispenses methadone, but also provides counseling, behavioral health services and other social support for patients to focus on their long-term ...
Methadone is a commonly used full-opioid agonist in the treatment of opioid use disorder. It is effective in relieving withdrawal symptoms and cravings in people with opioid addiction, and can also be used in pain control in certain situations. [ 131 ]
Methadone and LAAM are Schedule II narcotics approved for the same purpose within the highly regulated methadone clinic setting, usually known as an opioid treatment program (OTP). As of January 1, 2023, DATA 2000 requirements pertaining to special credentialing and registration with the DEA for the prescription of buprenorphine to treat opioid ...
Lane County Commissioners approved the new Oregon Recovery and Treatment Centers methadone clinic at 98 East 11th Ave. The ORTC must now get approval from the Oregon Health Authority, federal Drug ...
It involves "treatment of racemic methadone base with d-(+)-tartaric acid in an acetone/water mixture [which] precipitates almost solely the dextro-methadone levo-tartrate, and the more potent Levomethadone can easily be retrieved from the mother liquor in a high state of optical purity." [14]