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The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of January 3, 2020. [1]
Clobetasol is believed to work by activating steroid receptors. [8] Clobetasol propionate was patented in 1968 and came into medical use in 1978. [13] It is available as a generic medication. [10] In 2022, it was the 156th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [14] [15]
Clobetasol is a synthetic glucocorticoid corticosteroid. A propionate ester of clobetasol, clobetasol propionate , has also been marketed, and is far more widely used in comparison. [ 2 ] [ 3 ]
Note the propionate groups at the C17α and C21α positions (top right corner). This is a list of corticosteroid esters , including esters of steroidal glucocorticoids and mineralocorticoids . [ 1 ] [ 2 ] [ 3 ]
The agency is now scrambling to initiate California's first market tests for pesticides, sending a recent email warning license holders of coming "product embargos, voluntary and mandatory recalls ...
ATC code D07 Corticosteroids, dermatological preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.