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The San Antonio Contraceptive Study was a clinical research study published in 1971 about the side effects of oral contraceptives. Women coming to a clinic in San Antonio, Texas to prevent pregnancies were not told they were participating in a research study or receiving placebos. Ten of the women became pregnant while on placebos. [183] [184 ...
Unethical human experimentation. Unethical human experimentation is human experimentation that violates the principles of medical ethics. Such practices have included denying patients the right to informed consent, using pseudoscientific frameworks such as race science, and torturing people under the guise of research.
Henry Knowles Beecher (February 4, 1904 [1] – July 25, 1976 [2]) was a pioneering American anesthesiologist, medical ethicist, and investigator of the placebo effect at Harvard Medical School. An article by Beecher's in 1966 on unethical medical experimentation in the New England Journal of Medicine — "Ethics and Clinical Research" — was ...
Psychosurgery. 1880s. Psychosurgery (also called neurosurgery for mental disorder) has a long history. During the 1960s and 1970s, it became the subject of increasing public concern and debate, culminating in the US with congressional hearings. Particularly controversial was the work of Harvard neurosurgeon Vernon Mark and psychiatrist Frank ...
Scott Reuben (US), a former Professor of Anesthesiology at Tufts University, falsified and fabricated clinical trials involving painkiller medications. [164] [165] Reuben pleaded guilty in 2010 to one count of health care fraud and was sentenced to six months in prison. [166] As of 2023 Reuben has had 25 of his research publications retracted ...
Declaration of Helsinki. The Declaration of Helsinki (DoH, Finnish: Helsingin julistus) is a set of ethical principles regarding human experimentation developed originally in 1964 for the medical community by the World Medical Association (WMA). [1] It is widely regarded as the cornerstone document on human research ethics. [1][2][3][4]
The Nuremberg Code (German: Nürnberger Kodex) is a set of ethical research principles for human experimentation created by the court in U.S. v Brandt, one of the Subsequent Nuremberg trials that were held after the Second World War. Though it was articulated as part of the court's verdict in the trial, the Code would later become significant ...
Abdullahi v. Pfizer, Inc. The Kano trovafloxacin trial litigation arose out of a clinical trial conducted by the pharmaceutical company Pfizer in 1996 in Kano, Nigeria, during an epidemic of meningococcal meningitis. To test its new antibiotic, trovafloxacin (Trovan), Pfizer gave 100 children trovafloxacin, while another 100 received the gold ...