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A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1] [2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells . [ 2 ]
Nevus (pl.: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. [1] The term originates from nævus , which is Latin for " birthmark "; however, a nevus can be either congenital (present at birth) or acquired.
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocytes, or (2) nevus cells, a form of melanocyte that lack dendritic processes. [78] [79] Acral nevus (melanocytic nevus of acral skin, melanocytic nevus with intraepidermal ascent of cells) Amelanotic blue nevus (hypomelanotic blue nevus) Becker's nevus; Balloon ...
Congenital melanocytic nevi may be divided into the following types: [6]: 690–1 Small-sized congenital melanocytic nevus is defined as having a diameter less than 2 cm (0.79 in). [6]: 690 Medium-sized congenital melanocytic nevus is defined as having a diameter more than 2 cm (0.79 in) but less than 20 cm (7.9 in). [6]: 690
A connective tissue nevus is a skin lesion which may be present at birth or appear within the first few years of life. It is elevated, soft to firm in consistency, varying in size from 0.5 to several centimeters in diameter, and may manifest as grouped, linear, or irregularly-distributed lesions.
The prevalence of acral nevi increases directly with degree of skin pigmentation. In a study, palmar or plantar nevi were detected in 42.0% of black (50 of 119) vs 23.0% of whites (79 of 343). Palmar or plantar nevi of 6 mm diameter or larger were detected in 3.4% of blacks (4 of 119) vs 0.6% of whites. [2]
Congenital melanocytic nevus is a type of melanocytic nevus, the medical term for what is colloquially called a "mole", found in infants at birth. Occurring in about 1% of infants in the United States, it is located in the area of the head and neck 15% of the time, but may occur anywhere on the body. It may appear as light brown in fair-skinned ...