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Nucleic acid amplification tests (NAATs) tests find the genetic material (DNA) of Chlamydia bacteria. These tests are the most sensitive tests available, meaning they are very accurate and are unlikely to have false-negative test results. A polymerase chain reaction (PCR) test is an example of a nucleic acid amplification test. This test can ...
If left untreated, chlamydia in men can spread to the testicles causing epididymitis, which in rare cases can lead to sterility if not treated. [15] Chlamydia is also a potential cause of prostatic inflammation in men, although the exact relevance in prostatitis is difficult to ascertain due to possible contamination from urethritis. [19]
Mycoplasma genitalium (also known as MG [3], Mgen, or since 2018, Mycoplasmoides genitalium [1]) is a sexually transmitted, [4] small and pathogenic bacterium that lives on the mucous epithelial cells of the urinary and genital tracts in humans. [5] Medical reports published in 2007 and 2015 state that Mgen is becoming increasingly common.
Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. [1] Several hundred species of papillomaviruses, traditionally referred to as "types", [2] have been identified infecting all carefully inspected mammals, [2] but also other vertebrates such as birds, snakes, turtles and fish.
DNA damages cause changes in the structure of the genetic material and prevents the replication mechanism from functioning and performing properly. [1] The DNA damage response (DDR) is a complex signal transduction pathway which recognizes when DNA is damaged and initiates the cellular response to the damage. [2] DNA damage and mutation have ...
Genetic instability can originate due to deficiencies in DNA repair, or due to loss or gain of chromosomes, or due to large scale chromosomal reorganizations. Losing genetic stability will favour tumor development, because it favours the generation of mutants that can be selected by the environment.
Traditional DNA analysis was largely limited to samples that contained genetic material from a couple of people, said Monica Ghannam, a forensic scientist who testified in the Caneiro hearing ...
A loss in the repair systems for DNA double-stranded breaks and eroded telomeres can allow chromosomal rearrangements that generate loss, amplification and/or exchange of chromosome segments. [2] Some inherited genetic predispositions to cancer are the result of mutations in machinery that responds to and repairs DNA double-stranded breaks.