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Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
Fipronil acts as an insecticide with contact, and stomach action. It is sparingly soluble in water and is stable at normal temperatures for one year. Fipronil is an extremely active molecule and is a potent disruptor of the insect central nervous system. [5] Fipronil bait is more effective and kills faster than Hydramethylnon.
Chemical structure of fipronil, a common phenylpyrazole insecticide. Phenylpyrazole insecticides are a class of chemically-related broad-spectrum insecticides. [1] The chemical structures of these insecticides are characterized by a central pyrazole ring with a phenyl group attached to one of the nitrogen atoms of the pyrazole.
Hydramethylnon (AC 217,300) is an insecticide used primarily in the form of baits for cockroaches and ants. [1] [2] [3] It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation (IRAC class 20A).
Imiprothrin is a synthetic pyrethroid insecticide.It is an ingredient in some commercial and consumer insecticide products for indoor use. It has low acute toxicity to humans through the inhalation and dermal routes, but to insects it acts as a neurotoxin causing paralysis.
Spinosad is an insecticide based on chemical compounds found in the bacterial species Saccharopolyspora spinosa. The genus Saccharopolyspora was discovered in 1985 in isolates from crushed sugarcane. The bacteria produce yellowish-pink aerial hyphae, with bead-like chains of spores enclosed in a characteristic hairy sheath. [4]
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