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Syntometrine may enhance the blood pressure raising effect of vasoconstrictors (medicines given to constrict the blood vessels). Some inhaled anaesthetics used for general anesthesia, such as cyclopropane and halothane, may reduce the effect of oxytocin and ergometrine. There may also be an increased risk of a drop in blood pressure and ...
551 11998 Ensembl ENSG00000101200 ENSMUSG00000037727 UniProt P01185 P35455 RefSeq (mRNA) NM_000490 NM_009732 RefSeq (protein) NP_000481 NP_033862 Location (UCSC) Chr 20: 3.08 – 3.08 Mb Chr 2: 130.42 – 130.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized ...
Oxytocin is relatively safe when used at recommended doses, and side effects are uncommon. [14] These maternal events have been reported: [14] Subarachnoid hemorrhage; Increased blood pressure; Cardiac arrhythmia including increased or decreased heart rate, and premature ventricular contraction; Impaired uterine blood flow; Pelvic hematoma ...
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Hyponatremia is a decreased concentration of sodium in the body as a result of increased fluids. This occurs due to oxytocin's similar structure to vasopressin (antidiuretic hormone), which acts to retain water in the body. Hypotension, or low blood pressure, is also a common side effect due to oxytocin's ability to relax smooth muscle of vessels.
Effect Source Oxytocin: OT, OXY Uterus, mammary glands: Uterine contractions; lactation: supraoptic and paraventricular nuclei: Vasopressin: Arginine vasopressin, antidiuretic hormone VP, AVP, ADH Kidneys and arterioles: Stimulates water retention; raises blood pressure by contracting arterioles supraoptic and paraventricular nuclei
Parvocellular vasopressin cells, which project to many points in the hypothalamus and limbic system, as well as to the brainstem and spinal cord (these are involved in blood pressure and temperature regulation), and brown fat thermogenesis. Parvocellular CRH neurons, which are thought to be involved in stress-related behaviors.
In 1950, Geoffrey Harris and Barry Cross outlined the oxytocin pathway by studying oxytocin release in response to electrical stimulation. [24] In 1974, Walters and Hatton investigated the effect of water dehydration by electrically stimulating the supraoptic nucleus—the hypothalamic center responsible for the release of vasopressin. [ 24 ]