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Hyperlipidemia predisposes a person to atherosclerosis. Atherosclerosis is the accumulation of lipids, cholesterol, calcium, fibrous plaques within the walls of arteries. [61] This accumulation narrows the blood vessel and reduces blood flow and oxygen to muscles of the heart.
The lipid hypothesis (also known as the cholesterol hypothesis) is a medical theory postulating a link between blood cholesterol levels and the occurrence of cardiovascular disease. A summary from 1976 described it as: "measures used to lower the plasma lipids in patients with hyperlipidemia will lead to reductions in new events of coronary ...
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [ 9 ]
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood).
George V. Mann was an American medical researcher, physician, academic, and author known for his research on cholesterol's impact on cardiovascular health.He served as an assistant professor at Harvard University early in his career and as a professor and researcher of medicine and biochemistry at Vanderbilt University until his retirement.
The journal is published in print and online. As of February 1, 2019, its editors-in-chief are Kerry-Anne Rye and Nick Davidson. [3] The journal was established in response to the lack of published methodologies in lipid research as perceived by Edward H. Ahrens, Jr., Donald Zilversmit, and others, who founded Lipid Research Inc. to publish the ...
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
Remnant cholesterol is composed primarily of VLDL, IDL and chylomicron remnants. Remnant cholesterol, also known as remnant lipoprotein and triglyceride-rich lipoprotein cholesterol is an atherogenic lipoprotein composed primarily of very low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL) with chylomicron remnants.