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Anterograde transport is often the transportation from the cell body to the periphery of the neuron whereas retrograde transport brings organelles and vesicles away from the axon terminus to the cell body. Anterograde transport is regulated by kinesins, a class of motor proteins. Kinesins have two head domains which work together like feet ...
TEM of rat kidney tissue shows a protein dense tight junction (three dark lines) at ~55,000x magnification.. Tight junctions provide endothelial and epithelial cells with barrier function, which can be further subdivided into protective barriers and functional barriers serving purposes such as material transport and maintenance of osmotic balance.
The chloride potassium symporter is a membrane transport protein of the solute carrier family 12 that is present in the S3-segment of the renal proximal tubule [1] and in the neuron. [2] It functions in renal chloride reabsorption to transport chloride across the basolateral membrane . [ 1 ]
As suggested by its functions, this antiporter is located in the kidney for sodium reabsorption regulation and in the heart for intracellular pH and contractility regulation. NHE plays an important role in the nephron of the kidney, especially in the cells of the proximal convoluted tubule and collecting duct.
Tubular secretion occurs at Proximal Convoluted Tubule (PCT) and Distal Convoluted Tubule (D.C.T); for example, at proximal convoluted tubule, potassium is secreted by means of sodium-potassium pump, hydrogen ion is secreted by means of active transport and co-transport, i.e. anti-porter, and ammonia diffuses into renal tubule.
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The transport of glucose across the proximal tubule cell membrane involves a complex process of secondary active transport (also known as co-transport). [3] This process begins with the Na + /K + ATPase on the basolateral membrane. This enzyme uses ATP to pump 3 sodium ions out of the cell into the blood while bringing 2 potassium ions into the ...
The proximal convoluted tubule of the nephron has protein channels that reabsorb glucose, and others that secrete para-aminohippuric acid (PAH). However, its ability to do so is proportionate to the channel proteins available for the transport. [citation needed] Glucose is not secreted, so excretion = filtration - reabsorption. Both filtration ...