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  2. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    The long elimination half-life of dutasteride should be taken into consideration in the event of an overdose of the medication. [50] Dutasteride has been used in clinical studies at doses of up to 40 mg/day for a week (80 times the therapeutic dosage) and 5 mg/day for 6 months (10 times the therapeutic dosage) with no significant safety ...

  3. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    A 2017 population-based, matched-cohort study of 93,197 men aged 66 years and older with BPH found that finasteride and dutasteride were associated with a significantly increased risk of depression (HR Tooltip Hazard ratio, 1.94; 95% CI Tooltip Confidence interval, 1.73–2.16) and self-harm (HR, 1.88; 95% CI, 1.34–2.64) during the first 18 ...

  4. I'm a cardiologist and I want women to stop doing these 6 ...

    www.aol.com/im-cardiologist-want-women-stop...

    Other health conditions common in women can increase risk of heart disease, including migraine, polycystic ovarian syndrome, lupus, rheumatoid arthritis, psoriasis and inflammatory bowel disease.

  5. Discovery and development of 5α-reductase inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [ 4 ] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration.

  6. Most women older than 65 don't need to stop hormone therapy ...

    www.aol.com/lifestyle/most-women-older-65-dont...

    Now, new research finds that women who use hormone therapy after age 65 are usually fine to do just that — but the dose and timing of the treatment matter. The study, which was published in ...

  7. Losing Weight After 50 Is Possible: 21 Effective Tips From ...

    www.aol.com/losing-weight-50-possible-21...

    Find out how age and weight go together, here. Plus, expert tips for losing weight after 50, including diet plans, calorie needs, and low-impact workouts.

  8. Bicalutamide - Wikipedia

    en.wikipedia.org/wiki/Bicalutamide

    [39] [40] It is available in 50 mg, 80 mg (in Japan), [48] and 150 mg tablets for oral administration. [ 82 ] [ 83 ] The drug is registered for use as a 150 mg/day monotherapy for the treatment of LAPC in at least 55 countries, [ 2 ] with the U.S. being a notable exception where it is registered only for use at a dosage of 50 mg/day in ...

  9. Worth $15 Million, Not Yet 50, And Mentally Done With Work ...

    www.aol.com/worth-15-million-not-yet-235538313.html

    Key Points. If you have $15 million and are tired of working, you should explore your options. You likely have plenty of money to retire, even at a young age.