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Signs of platelet dysfunction such as petechiae or ecchymosis, epistaxis or rhinorrhagia and in severe cases with haematuria; gingival or ocular haemorrhages are used to identify and diagnose thrombocytopaenia. Up to half of dogs may present with splenomegaly. [2] [8] [1]
TAR syndrome (thrombocytopenia with absent radius) is a rare genetic disorder that is characterized by the absence of the radius bone in the forearm and a dramatically reduced platelet count. [1] It is associated with cardiac defects, dysmorphic features, and petechiae.
Thrombotic thrombocytopenic purpura (TTP) initially presents with a range of symptoms that may include severe thrombocytopenia (platelet count usually < 30,000/mm³), microangiopathic hemolytic anemia (evidenced by schistocytes in the blood smear), and various clinical signs such as petechiae, purpura, neurologic symptoms, myocardial ischemia ...
One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]
ITP can be difficult to distinguish from gestational thrombocytopenia (which is by far the most common cause of thrombocytopenia in pregnancy). Unlike ITP, the platelet count in gestational thrombocytopenia rarely goes below 100,000, and a platelet count below 80,000 is even more rare (seen in less than 0.1% of cases of gestational ...
Leptospirosis is a blood infection caused by the bacterium Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe (bleeding in the lungs or meningitis). [5]
Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare autosomal recessive bone marrow failure syndrome characterized by severe thrombocytopenia, which can progress to aplastic anemia and leukemia. [4] CAMT usually manifests as thrombocytopenia in the initial month of life or in the fetal phase.
Symptoms include lethargy, weakness, depression, pale mucous membranes, fever, and blood in the urine. Hypoxia may lead to forebrain disease, increased heart rate and respiratory rate, and liver or kidney disease. Animals suffering from this disease must be taken to a veterinarian immediately. Treatment includes fluid support and blood ...