Search results
Results From The WOW.Com Content Network
Vestronidase alfa (Mepsevii) is a recombinant human lysosomal beta glucuronidase for MPS VII (Sly syndrome) approved in the United States in November 2017 . [9] Bone marrow transplantation (BMT) and umbilical cord blood transplantation (UCBT) have had limited success in treating the mucopolysaccharidoses. Abnormal physical characteristics ...
Vets have also prescribed expectorant cough tablets to help loosen the mucus in sick dogs, and some are using oxygen chambers and nebulizers to provide some relief, dog owners have said.
Sly syndrome, also called mucopolysaccharidosis type VII (MPS-VII), is an autosomal recessive lysosomal storage disease caused by a deficiency of the enzyme β-glucuronidase. This enzyme is responsible for breaking down large sugar molecules called glycosaminoglycans (AKA GAGs, or mucopolysaccharides).
Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease and has use in veterinary medicine. [1] It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain ...
Mucopolysaccharidosis type I is a spectrum of diseases in the mucopolysaccharidosis family. It results in the buildup of glycosaminoglycans (or GAGs, or mucopolysaccharides) due to a deficiency of alpha-L iduronidase , an enzyme responsible for the degradation of GAGs in lysosomes .
The tell-tale signs of walking pneumonia are not obvious. Illnesses caused by mycoplasma pneumoniae tend to be milder than infections caused by the more common bacterial pneumonia, streptococcus ...
Pneumonia is an irritation of the lungs caused by different sources. It is characterized by an inflammation of the deep lung tissues [1] and the bronchi. Pneumonia can be acute or chronic. [2] This life-threatening [3] illness is more common in cats than in dogs [1] and the complication “Kennel Cough” [1] can occur in young pets.
Mice and dogs with MPS I have been successfully treated with gene therapy. Most vectors can correct the disease in the liver and spleen, and can correct brain effects with a high dosage. Gene therapy has improved survival, neurological, and physical symptoms; however, some animals have developed unexplained liver tumors.