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Nicotine gum is a chewing gum containing a small dose of nicotine polacrilex. [1] It is classified as a short-acting (also called fast-acting) form of NRT because it relieves the cravings and symptoms that occur with smoking cessation more quickly than a long-acting NRT (i.e., the nicotine patch).
Nicotine gum is contraindicated in individuals with temporomandibular joint disease. [79] People with chronic nasal disorders and severe reactive airway disease require additional precautions when using nicotine nasal sprays. [73] Nicotine in any form is contraindicated in individuals with a known hypersensitivity to nicotine. [79] [73]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
More research is needed on the effects in younger people, but adult use of nicotine carries a cardiovascular risk, raises the risk of cancer and can cause bad breath, tooth loss and gum disease.
Nicotine products like gum and mints — which some people use to help curb their addition and eventually quit smoking and vaping — are the “least harmful” way to consume nicotine ...
Nicotine pouches are used by placing them between your upper or lower lip and gum. "The nicotine is absorbed through the mouth into the bloodstream," Keller-Hamilton says. “Nicotine delivery ...
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