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  2. Antiarrhythmic agent - Wikipedia

    en.wikipedia.org/wiki/Antiarrhythmic_agent

    The five main classes in the Vaughan Williams classification of antiarrhythmic agents are: Class I agents interfere with the sodium (Na +) channel. Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers. Class III agents affect potassium (K +) efflux. Class IV agents affect calcium channels and ...

  3. ATC code C01 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_C01

    [1] [2] [3] Subgroup C01 is part of the anatomical group C Cardiovascular system. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QC01. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.

  4. List of cardiac pharmaceutical agents - Wikipedia

    en.wikipedia.org/wiki/List_of_cardiac...

    Class of antihypertensives that bind to and inhibit the angiotensin II receptor type 1 and thereby block the arteriolar contraction and sodium retention effects of renin–angiotensin system. Azilsartan medoxomil

  5. Category:Antiarrhythmic agents - Wikipedia

    en.wikipedia.org/wiki/Category:Antiarrhythmic_agents

    Sodium channel blockers (1 C, 77 P) Pages in category "Antiarrhythmic agents" The following 59 pages are in this category, out of 59 total.

  6. Sodium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Sodium_channel_blocker

    Class Ic antiarrhythmic agents markedly depress the phase 0 depolarization (decreasing V max). They decrease conductivity, but have a minimal effect on the action potential duration. Of the sodium channel blocking antiarrhythmic agents (the class I antiarrhythmic agents), the class Ic agents have the most potent sodium channel blocking effects.

  7. Cardiac Arrhythmia Suppression Trial - Wikipedia

    en.wikipedia.org/wiki/Cardiac_Arrhythmia...

    The second Cardiac Arrhythmia Suppression Trial (CAST II) modified the enrollment criteria to include patients at higher risk for serious arrhythmia. [4] This included 1) patients enrolled within 4 to 90 days of a previous MI, 2) a left ventricular ejection fraction lower than 40%, 3) prior to enrollment, suppression of PVCs had occurred with the drugs (vs. placebo) using a double-blinded ...

  8. Lorcainide - Wikipedia

    en.wikipedia.org/wiki/Lorcainide

    Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac [1] and Wolff–Parkinson–White syndrome. [2]

  9. Pharmacological cardiotoxicity - Wikipedia

    en.wikipedia.org/wiki/Pharmacological_cardiotoxicity

    [1] Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]