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A chancre (/ ˈ ʃ æ ŋ k ər / SHANG-kər) [1] is a painless genital ulcer most commonly formed during the primary stage of syphilis. [2] This infectious lesion forms around 21 days after the initial exposure to Treponema pallidum , the gram-negative spirochaete bacterium causing syphilis, but can range from 10 to 90 days. [ 2 ]
Chancre on a penis due to primary syphilis, 1978. Primary syphilis is typically acquired by direct sexual contact with the infectious lesions of another person. [19] Approximately 2–6 weeks after contact (with a range of 10–90 days) a skin lesion, called a chancre, appears at the site and this contains infectious bacteria.
File: Chancres on the penile shaft due to a primary syphilitic infection caused by Treponema pallidum 6803 lores.jpg
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The initial ulcer may be mistaken as a "hard" chancre, the typical sore of primary syphilis, as opposed to the "soft chancre" of chancroid. [citation needed] Approximately one-third of the infected individuals will develop enlargements of the inguinal lymph nodes, the nodes located in the fold between the leg and the lower abdomen. [citation ...
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Some infants with congenital syphilis have symptoms at birth, but many develop symptoms later. Symptoms may include rash, fever, large liver and spleen, and skeletal abnormalities. [17] Newborns will typically not develop a primary syphilitic chancre but may present with signs of secondary syphilis (i.e. generalized body rash).