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Tigan, Tebamide: AHFS/Drugs.com: Monograph: MedlinePlus: a682693: Routes of ... Tigan) is an antiemetic used to prevent nausea and vomiting. Mechanism of action
An antiemetic is a drug that is effective against vomiting and nausea.Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.
Pipamazine (INN; trade names Mornidine, Mometine, Nausidol) is a drug of the phenothiazine class formerly used as an antiemetic.It is chemically related to chlorpromazine, but has negligible antipsychotic activity and produces few extrapyramidal side effects.
The vomiting center of the brain refers to the groups of loosely organized neurons in the medulla that include the CTZ within the area postrema and the nucleus tractus solitarii. [2] One of the ways the chemoreceptor trigger zone implements its effects on the vomiting center is by activation of the opioid mu receptors and delta receptors. [6]
Nausea and vomiting associated with migraine headaches respond best to dopamine antagonists such as metoclopramide, prochlorperazine, and chlorpromazine. [22] In cases of gastroenteritis, serotonin antagonists such as ondansetron were found to suppress nausea and vomiting, as well as reduce the need for IV fluid resuscitation. [ 22 ]
Drug reaction (vomiting may occur as an acute somatic response to): [citation needed] Alcohol, which can be partially oxidized into acetaldehyde that causes the symptoms of hangover, including nausea, vomiting, shortness of breath, and fast heart rate. [22] Opioids; Selective serotonin reuptake inhibitors; Many chemotherapy drugs
Nausea and vomiting can be extremely distressing for patients, and so is one of their major concerns. [10] Vomiting has been associated with major complications, such as pulmonary aspiration of gastric content, and might endanger surgical outcomes after certain procedures, for example after maxillofacial surgery with wired jaws.
Vomiting excessive amounts of alcohol is an attempt by the body to prevent alcohol poisoning and death. Vomiting may also be caused by other drugs, such as opiates, or toxins found in some foods and plants. Food allergies and sensitivities, such as lactose intolerance, can cause vomiting. [2] Morning sickness may have a defensive purpose. One ...