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Cell potency is a cell's ability to differentiate into other cell types. [1] [2] The more cell types a cell can differentiate into, the greater its potency.Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally ...
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Embryonic stem cells of the inner cell mass are pluripotent, meaning they are able to differentiate to generate primitive ectoderm, which ultimately differentiates during gastrulation into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm.
The liver receptor homolog-1 (LRH-1) also known as totipotency pioneer factor NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. [ 5 ] [ 6 ] LRH-1 is a member of the nuclear receptor family of intracellular transcription factors .
Induced pluripotent stem cells were first generated by Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University, Japan, in 2006. [1] They hypothesized that genes important to embryonic stem cell (ESC) function might be able to induce an embryonic state in adult cells.
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Cellular differentiation is an essential function of the archaeocyte. All specialized cells within the sponge have its origins with the archaeocyte. This is especially important in reproduction as the sex cells of the sponge in sexual reproduction are formed from these amoeboid cells.
Transdifferentiation refers to the conversion of one cellular phenotype to another. [21] This phrase defines the overview of what dedifferentiation contributes to cell fates; firstly, dedifferentiation brings the cell back up the epigenetic landscape, [ 22 ] and then the cell can “roll” down a new valley, thus re-differentiating into a new ...