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Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis. In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system.
Changes in sexual health: Lower estrogen levels can lead to low libido, more trouble achieving orgasm and vaginal dryness, which can cause burning and pain during sex, Tang says. Many women find ...
A June 2023 study by the Mayo Clinic estimated an annual loss of $1.8 billion in the United States due to workdays missed as a result of menopause symptoms. [122] This was one of the largest studies to date examining the impact of menopause symptoms on work outcomes.
Menopause is a natural biological process. For some, it happens in their 40s while others start later in life in their 50s (the average age is 51 in the United States, according to Mayo Clinic).
Type 1 is the most common, can be associated with estrogen therapy, and is usually low grade. Type 2 is not related to estrogen stimulation and usually higher grade and poorer in prognosis. [ 53 ] The endometrial hyperplasia that leads to endometrial cancer with estrogen therapy can be prevented by concomitant administration of progestogen . [ 53 ]
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In others, particularly with coexistent depression, symptoms such as decreased quality of life can be severe. [9] Hormonally, POI is defined by abnormally low levels of estrogen and high levels of FSH, which demonstrate that the ovaries are no longer responding to circulating FSH by producing estrogen and developing fertile eggs. The ovaries ...