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A blue stained (with isosulfan blue) sentinel lymph node in the axilla. A micrograph showing an adenocarcinoma of the breast (dark pink) in a lymph node (purple) and extending into the surrounding fat (white, chicken-wire appearance). H&E stain. There are various procedures entailing the sentinel node detection: Preoperative planar ...
The first draining lymph node, the "sentinel", represents an existing or non-existing tumour of an entire lymph node region. The method has been validated using radionuclides and/or blue dye for breast cancer, malignant melanoma and also gastrointestinal tumours and gives a good detection rate and sensitivity.
For clinical stages I and II breast cancer, axillary lymph node dissection should only be performed after first attempting sentinel node biopsy. [4] If cancer cells are found in the nodes, it increases the risk of metastatic breast cancer. Another method of determining breast cancer spread is to perform an endoscopic axillary sentinel node biopsy.
This page was last edited on 11 February 2014, at 20:22 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
The general location of the sentinel node is determined with the use of a handheld scanner with a gamma-sensor probe that detects the technetium-99m–labeled tracer that was previously injected around the biopsy site. An injection of Methylene blue or isosulfan blue is done at the same time to dye any draining nodes visibly blue. An incision ...
Bamboo sign; Banana sign; Bat wing appearance; Bear paw sign; Beveled edge sign; Bird of prey sign; Bite sign; Black pleura sign; Blade of grass sign (also known as Flame sign); Blumensaat's line
The sentinel node market experienced high growth in the early and mid-1990s, starting with melanoma sentinel node surgical search and breast cancer sentinel node staging; both are currently considered standards of care. [4] The use of a radioactive tracer, rather than a coloured dye, was proposed in 1984. [5] [6]
Sentinel, a paradigm role in Final Fantasy XIII; Sentinel, a character class in the Mass Effect universe; Alan Scott, the original Green Lantern, who was called "sentinel" at one point; Sentinels, a faction in Call of Duty: Advanced Warfare; Sentinel, a computer in the TV show Transformers: Beast Wars
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