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The popular name "mitochondrial Eve", of 1980s coinage, [17] has contributed to a number of popular misconceptions. At first, the announcement of a "mitochondrial Eve" was even greeted with endorsement from young earth creationists, who viewed the theory as a validation of the biblical creation story. [39] [40] [41] [non-primary source needed]
In human mitochondrial genetics, L is the mitochondrial DNA macro-haplogroup that is at the root of the anatomically modern human (Homo sapiens) mtDNA phylogenetic tree. As such, it represents the most ancestral mitochondrial lineage of all currently living modern humans, also dubbed "Mitochondrial Eve". Its two sub-clades are L1-6 and L0.
The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the mitochondrial molecular clock. It is an area of ...
Mitochondrial DNA (mtDNA) is nearly immune to sexual mixing, unlike the nuclear DNA whose chromosomes are shuffled and recombined in Mendelian inheritance. Mitochondrial DNA, therefore, can be used to trace matrilineal inheritance and to find the Mitochondrial Eve (also known as the African Eve), the most recent common ancestor of all humans ...
The title of the book comes from one of the principal achievements of mitochondrial genetics, which is the classification of all modern Europeans into seven groups, the mitochondrial haplogroups. Each haplogroup is defined by a set of characteristic mutations on the mitochondrial genome, and can be traced along a person's maternal line to a ...
Mitochondrial Inheritance Patterns. In human mitochondrial genetics, there is debate over whether or not paternal mtDNA transmission is possible. Many studies hold that paternal mtDNA is never transmitted to offspring. [8] This thought is central to mtDNA genealogical DNA testing and to the theory of mitochondrial Eve.
The finding that "Mitochondrial Eve" was relatively recent and African seemed to give the upper hand to the proponents of the Out of Africa hypothesis.But in 2002, Alan Templeton published a genetic analysis involving other loci in the genome as well, and this showed that some variants that are present in modern populations existed already in Asia hundreds of thousands of years ago. [31]
Mitochondrial replication is controlled by nuclear genes and is specifically suited to make as many mitochondria as that particular cell needs at the time. Mitochondrial transcription in humans is initiated from three promoters, H1, H2, and L (heavy strand 1, heavy strand 2, and light strand promoters). The H2 promoter transcribes almost the ...