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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [ 1 ] [ 2 ] [ 3 ] It is either taken by mouth or applied to the skin as a cream or ointment.
Antifungals that have been studied and found to be effective in the treatment of seborrhoeic dermatitis include ketoconazole, fluconazole, miconazole, bifonazole, sertaconazole, clotrimazole, flutrimazole, ciclopirox, terbinafine, butenafine, selenium disulfide, and lithium salts such as lithium gluconate and lithium succinate. [10] [3]
Oral terbinafine is better tolerated than itraconazole. [28] For superficial white onychomycosis, systemic rather than topical antifungal therapy is advised. [29] Topical agents include ciclopirox nail paint, amorolfine, and efinaconazole. [30] [31] [32] Some topical treatments need to be applied daily for prolonged periods (at least one year ...
Kerion or kerion celsi is an acute inflammatory process which is the result of the host's response to a fungal ringworm infection of the hair follicles of the scalp (occasionally the beard) that can be accompanied by secondary bacterial infection(s).
Numerous studies have found Tinea capitis to be the most prevalent dermatophyte to infect children across the continent of Africa. [32] Dermatophytosis has been found to be most prevalent in children ages 4 to 11, infecting more males than females. [32] Low socioeconomic status was found to be a risk factor for Tinea capitis. [32]
Archaeologists used radiocarbon dating to date one mass grave to between the late 1400s and early 1600s, and found shards of pottery and coins dating from the later end of that range at the site.
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
Like the allylamine antifungals (e.g terbinafine), butenafine works by inhibiting the synthesis of ergosterol by binding to and inhibiting squalene epoxidase, an enzyme in the pathway used for creation of the sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak ...