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Dutasteride is the generic name of the drug Avodart and its international nonproprietary name, United States Adopted Name, British Approved Name, and Japanese Accepted Name. [ 71 ] Brand names
Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer. [11] [12] Epristeride (brand names Aipuliete, Chuanliu) is marketed in China for the treatment of benign prostatic hyperplasia.
It contains 0.5 mg of dutasteride and 0.4 mg of tamsulosin hydrochloride. [2] Jalyn was the result of the CombAT (Combination of Avodart and Tamsulosin) trial of 2008. It was approved by the U.S. Food and Drug Administration (FDA) on June 14, 2010. [4]
Men, the odds are stacked against you. By age 35, around two-thirds of all American men will have begun to experience androgenetic alopecia, more commonly known as male pattern baldness. By age 50 ...
Drug treatments have not helped after 3 months, or they are unsafe for the person to use. ... dutasteride (Avodart) However, these options may not work for everyone, and a doctor or healthcare ...
An FDA-approved medication already used to treat people who have type 2 diabetes and chronic kidney disease may also help lower their stroke and heart attack risk, a new study has found.
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration. [1]
The results of the CombAT (combination of dutasteride [Avodart] and tamsulosin [Duodart]) trial in 2008 demonstrated that treatment with the combination of dutasteride and tamsulosin provides greater symptom benefits compared to monotherapy with either agent alone for treatment of benign prostatic hyperplasia. [17]