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Sjögren's syndrome can damage vital organs, with symptoms that may plateau or worsen, or go into remission, as with other autoimmune diseases. Some people may experience only the mild symptoms of dry eyes and mouth, while others have symptoms of severe disease. Many patients can treat problems symptomatically.
Immunofluorescence pattern of SS-A and SS-B antibodies. Produced using serum from a patient on HEp-20-10 cells with a FITC conjugate. Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA, anti–SS-A/Ro, and anti-Ro/SS-A) are a type of anti-nuclear autoantibodies that are associated with ...
Henrik Samuel Conrad Sjögren (UK: / ˈʃɜːɡrɛn /, US: / ˈʃoʊɡrɛn /, [1] Swedish: [ˈɧø̂ːɡreːn]; [2] 23 July 1899, Köping – 17 September 1986, Lund) [3] was a Swedish ophthalmologist best known for describing the eponymous condition Sjögren syndrome. Sjögren received his medical degree in Stockholm in 1927. His first ...
Sjögren–Larsson syndrome is a rare autosomal recessive form of ichthyosis with neurological symptoms. [1]: 485 [2]: 564 [3] It can be identified by a triad of medical disorders. The first is ichthyosis, which is a buildup of skin to form a scale-like covering that causes dry skin and other problems. The second identifier is paraplegia which ...
About Sjögren’s Disease Sjögren’s disease is a chronic autoimmune disease characterized by the production of autoantibodies, chronic inflammation and lymphocytic infiltration of the exocrine glands. Systemic effects are common and impact the lungs, kidneys and nervous system in addition to extensive dryness, profound fatigue and chronic pain.
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D12151. Ianalumab (INN; [1] development code VAY736) is a monoclonal antibody that is being investigated for autoimmune hepatitis, multiple sclerosis, pemphigus vulgaris, rheumatoid arthritis, Sjögren syndrome, and systemic lupus erythematosus. [2][3][4] This drug is being developed by Novartis. In 2021 ianalumab was undergoing Phase II / III ...
A deficiency in zinc mainly results in skin disorders in adult cats, but also results in growth oddities. The skin of a cat deficient in zinc would likely have erythema and hair loss. The cat may have crusty, scaly skin on its limbs or tail. [1] The coat of the cat becomes dull. Similarly, copper can affect coat health of cats; deficiencies ...