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Flucloxacillin has similar pharmacokinetics, antibacterial activity, and indications to dicloxacillin, and the two agents are considered interchangeable. It is reported to have higher, though rare, incidence of severe hepatic adverse effects than dicloxacillin, [ 28 ] but a lower incidence of renal adverse effects.
Ampicillin/flucloxacillin also known as co-fluampicil (), and sold under the tradename Magnapen, is a combination drug of the two β-lactam antibiotics, ampicillin and flucloxacillin, both in equal amounts, available in a capsule and as a liquid, both taken by mouth, and as a formulation which can be given by injection into muscle or vein.
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.
Nausea (if alcohol taken concurrently) - if contains methylthiotetrazole side group; Hypoprothrombinemia - if contains methylthiotetrazole side group; Allergic reactions; Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Cefoxitin: Cefotetan: Cefotan: Cefamandole ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
Knowing the indication of the drug can also help providers determine if the dose of the drug is appropriate per indication, and this can greatly improve patient safety and drug effectiveness. [28] However, there are still some challenges with incorporating the indication of use on prescription drug labels.
Side effects include nausea, diarrhea, and allergic reactions including anaphylaxis. [1] Clostridioides difficile diarrhea may also occur. [2] It is not recommended in people who have previously had a penicillin allergy. [1] Use during pregnancy appears to be relatively safe. [1] Cloxacillin is in the penicillin family of medications. [2]
Dicloxacillin is similar in pharmacokinetics, antibacterial activity, and indications to flucloxacillin, and the two agents are considered interchangeable. [6] It is believed to have lower incidence of severe hepatic adverse effects than flucloxacillin, but a higher incidence of renal adverse effects.