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In situ follicular lymphoma is an accumulation of monoclonal B cells (i.e. cells descendent from a single ancestral cell) in the germinal centers of lymphoid tissue. These cells commonly bear a pathological genomic abnormality, i.e. a translocation between position 32 on the long (i.e. "q") arm of chromosome 14 and position 21 on chromosome 18's q arm.
Follicular lymphoma (FL) is a lymphoproliferative disorder generally associated with an indolent course. [12] It originates from follicular center B cells. [12] About 85% of cases show t(14;18)(q32;q21) chromosomal translocation, which causes the overexpression of the anti-apoptotic protein Bcl-2. [13]
T follicular helper cells mediate the germinal center reaction in two key ways. First, T follicular helper cells express CD40L, which is a tumor necrosis factor (TNF) cytokine that binds the CD40 molecule expressed on GC B cells. This interaction upregulates the NF-kB signaling pathway, which stimulates the division of GC B cells. Second, T ...
Duodenal-type follicular lymphoma (DFL) is a form of lymphoma in which certain lymphocyte types, the B-cell-derived centrocytes and centroblasts, form lymph node follicle-like structures principally in the duodenum and other parts of the small intestine. It is an indolent disease which on rare occasions progresses to a more aggressive lymphoma ...
Whatever your reason for taking notice in the bathroom, if you have concerns about changes in poop color or consistency (from diarrhea to constipation), experts say it’s important to put aside ...
Gallbladder Cancer: It’s uncommon, but it can happen and can affect the color of stool. Gallbladder cancer doesn’t always start with gallstones, although it can; here are 7 other symptoms of ...
Follicular dendritic cell sarcoma (FDCS) is an extremely rare neoplasm.While the existence of FDC tumors was predicted by Lennert in 1978, the tumor wasn't fully recognized as its own cancer until 1986 after characterization by Monda et al. [1] [2] It accounts for only 0.4% of soft tissue sarcomas, but has significant recurrent and metastatic potential and is considered an intermediate grade ...
Steatorrhea refers to bulky, foul-smelling, oily stool that tends to be pale in color and float in the toilet bowl, resisting flushing. (These are the 9 most common reasons your poop is black .)