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Simufilam (PTI-125) is an experimental medication for the treatment of Alzheimer's disease. [2][3] It is being developed by the American pharmaceutical firm Cassava Sciences. The drug is in phase III clinical trials as of October 2023. There are two phase III clinical studies: RETHINK-ALZ, a 52-week trial, is set to complete in 2024, [4] and ...
145 912.34 g·mol −1. Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. [2][3] It is a monoclonal antibody [3][2] that targets aggregated forms (plaque) [4][5] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [6][7] It was developed ...
Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), [1] are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first drug in the class to be developed, in the early 2000s, is bapineuzumab, but it did not show effectiveness in later-stage trials. [2] The first drug to be approved by the US Food and Drug ...
August 24, 2024 at 11:00 PM. After a lull of nearly 2 decades, the Food and Drug Administration (FDA) has approved some novel drugs for the treatment of Alzheimer’s disease since 2021. Most of ...
The first Alzheimer’s drugs meant to slow the progression of the fatal disease may only be available to a tiny fraction of patients, a study published Wednesday in the journal Neurology suggests ...
Groundbreaking treatments for Alzheimer's disease that work by removing a toxic protein called beta amyloid from the brain may benefit whites more than Black Americans, whose disease may be driven ...
C6452H10038N1708O2013S42. Molar mass. 145 089.74 g·mol −1. Donanemab, sold under the brand name Kisunla, is a monoclonal antibody used for the treatment of Alzheimer's disease. [1][2] Donanemab was developed by Eli Lilly and Company. [3][4] The most common side effects include amyloid-related imaging abnormalities and headache.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.