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Women taking probiotics may see a reduction in the severity, frequency, and recurrence of bacterial vaginosis, a common infection that affects about 30 percent of women of childbearing age in the ...
L. casei has been combined with other probiotic strains of bacteria in randomized trials studying its effects in preventing antibiotic-associated diarrhea (AAD) and Clostridioides difficile infections (CDI), and patients in the trials who were not given the placebo had significantly lower rates of AAD or CDI (depending on the trial) with no ...
Meta-analyses have concluded that probiotics may protect against antibiotic-associated diarrhea in both children and adults. [2] [3] Evidence is insufficient, however, regarding an effect on rates of C. difficile colitis. [4] The efficacy of probiotic AAD prevention is dependent on the probiotic strain(s) used and on the dosage.
The potential efficacy of probiotics to treat AAD depends on the probiotic strains and dosage. [ 100 ] [ 101 ] One review recommended for children L. rhamnosus or Saccharomyces boulardii at 5 to 40 billion colony-forming units/day, given the modest number needed to treat and the likelihood that adverse events are very rare. [ 94 ]
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Although probiotics are considered safe, they may cause bacteria-host interactions and adverse health consequences. In certain cases there is a risk of bacteremia when probiotics are used. [9] [10] Currently, the probiotic strain, frequency, dose and duration of the probiotic therapies are not established. [9]