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The yardstick for human mortality from H5N1 is the case-fatality rate (CFR); the ratio of the number of confirmed human deaths resulting from infection of H5N1 to the number of those confirmed cases of infection with the virus. For example, if there are 100 confirmed cases of a disease and 50 die as a consequence, then the CFR is 50%.
The true fatality rate may be lower because some cases with mild symptoms may not have been identified as H5N1. [ 7 ] Confirmed human cases and mortality rate of avian influenza ( H5N1 ) 2003–2024
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
With reports of the first human death from bird flu in the US, some Americans are feeling an uncomfortable flashback to the early days of Covid-19, when infectious disease experts were talking ...
Most human cases of bird flu in North America have been mild, a fact that’s underscored by a new study of the first 46 confirmed human H5N1 infections in the United States this year.
Since March, the U.S. Centers for Disease Control and Prevention has said that 52 people have been infected by the H5N1 virus. Dairy cattle were the source for 30 of those cases, poultry for 21.
Highly pathogenic H5N1 avian influenza in a human appears to be far worse, killing over 50% of humans reported infected with the virus, although it is unknown how many cases (with milder symptoms) go unreported. In one case, a boy with H5N1 experienced diarrhea followed rapidly by a coma without developing respiratory or flu-like symptoms. [41]
Before H5N1 bird flu virus arrived in North America in 2021, the disease had been recognized as having potential to cause severe disease and death. H5N1 was first identified in wild geese in China ...