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MOPP is a combination chemotherapy regimen used to treat Hodgkin lymphoma. The acronym is derived from the component drugs of the regimen: ustargen (also known as mechlorethamine, chlormethine, mustine, nitrogen mustard, or MSD) ncovin (also known as Vincristine or VCR) rocarbazine (also known as Matulane or Natulan)
Tissue specimens from Hodgkin's seven cases were preserved at Guy's Hospital. Nearly 100 years after Hodgkin's initial publication, histopathologic reexamination confirmed Hodgkin lymphoma in only three of seven of these people. [81] The remaining cases included non-Hodgkin lymphoma, tuberculosis, and syphilis. [81]
relapsed non-Hodgkin's lymphoma and Hodgkin's lymphoma R-FCM or FCM-R: rituximab + FCM; that is, rituximab, fludarabine, cyclophosphamide, mitoxantrone: B cell non-Hodgkin lymphoma R-ICE or ICE-R or RICE: rituximab + ICE; that is, rituximab, ifosfamide, carboplatin, etoposide: high-risk progressive or recurrent lymphomas: RVD
An immunotherapy approach to treating advanced Hodgkin lymphoma may drastically increase patients’ chances of survival, including those as young as 12, according to a new clinical trial.
BEACOPP is a chemotherapy regimen for treatment of Hodgkin lymphoma developed by the German Hodgkin Study Group [1] used for patients in Stages > II or early (IA or IB) with unfavorable risk factors. [2] Patients typically receive treatment in cycles of 21 days with no drugs given on days 15–21. [3]
Treatment-related leukemias are uncommon with ABVD, especially as compared with MOPP. [4] However, one study found a risk of second cancers as high as 28% at 25 years after treatment for Hodgkin lymphoma, although most of the patients in this study were treated with MOPP chemotherapy rather than ABVD. [9]
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