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The Patient-Reported Outcomes Measurement Information System [1] (PROMIS) provides clinicians and researchers access to reliable, valid, and flexible measures of health status that assess physical, mental, and social well–being from the patient perspective. PROMIS measures are standardized, allowing for assessment of many patient-reported ...
There are efforts to define core sets of patient-relevant outcome variables to be measured in clinical trials in general [28] and for multi-modal pain therapy. [29] Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. [30]
In CMOP-E, occupational order has six perspectives – physical rehabilitative, psycho-emotional, socio-adaptive, neurointegrative, developmental or environmental – in relation to the arbitrary performance areas of self care, leisure and productivity. [2] [12] Quality of function is assessed in terms of both performance and satisfaction. [14]
Journal of the American Physical Therapy Association,64:1357-1360; Nichol, et al. (2011) Measuring Functional and Quality of Life Outcomes Following Major Head Injury: Common Scales and Checklists. Injury, Int J. 42:281-287; Rappaport, et al. (1982) Disability Rating Scale for Severe Head Trauma Patients: Coma to Community.
Over the years clinicians and researchers have moved away from physical and radiological endpoints towards patient-reported outcomes. However, using patient-reported outcomes does not solve the problem of small differences being statistically significant but possibly clinically irrelevant. [6]
This subversion has been the justification for repeated attempts to improve process and thus outcomes by reorganizing the structure of health care, wittily described by Oxman et al. [16] Donabedian himself cautioned that outcomes measurement cannot distinguish efficacy from effectiveness: (outcomes may be poor because the right treatment is ...
Outcomes measures should be relevant to the target of the intervention (be it a single person or a target population). [2] Depending on the design of a trial, outcome measures can be either primary outcomes, in which case the trial is designed around finding an adequate study size (through proper randomization and power calculation). [1]
Core outcome sets are commonly used by clinical investigators who conduct clinical trials for the treatment of a health condition. [2] [3] [4] The patient population associated with a particular core outcome set may vary, as some apply to all patients with that health condition and others apply to a small subset of that population. [2]