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Stress, hypometabolism, and oxidative damage may decrease physiologic reserve in the elderly and can lead to a decrease in neuron energy production and an increase in neuron damage. [12] Thioredoxin reductase is an antioxidant that neutralizes oxidative free radicals that can cause cell death. The brain is vulnerable to oxidative free radicals ...
Delirium (formerly acute confusional state, an ambiguous term that is now discouraged) [1] is a specific state of acute confusion attributable to the direct physiological consequence of a medical condition, effects of a psychoactive substance, or multiple causes, which usually develops over the course of hours to days.
Dementia affects 5% of the population older than 65 and 20–40% of those older than 85. [274] Rates are slightly higher in women than men at ages 65 and greater. [ 274 ] The disease trajectory is varied and the median time from diagnosis to death depends strongly on age at diagnosis, from 6.7 years for people diagnosed aged 60–69 to 1.9 ...
Woman with age-related dementia Age-related memory loss , sometimes described as "normal aging " (also spelled "ageing" in British English ), is qualitatively different from memory loss associated with types of dementia such as Alzheimer's disease , and is believed to have a different brain mechanism.
More likely in the elderly with pre-existing declining mental functions, termed mild cognitive impairment (MCI). [13] MCI is a transitional zone between normal mental function and evident Alzheimer's disease or other forms of dementia. It is insidious, and seldom recognized, except in retrospect after affected persons are evidently demented.
Menopause is a natural decline in the ovarian function of women who reach the age between 45 and 54 years. "About 25 million women pass through menopause worldwide each year, and it has been estimated that, by the year 2030, the world population of menopausal and postmenopausal women will be 1.2 billion, with 47 million new entrants each year ...
In Psychology, confusion is the quality or emotional state of being bewildered or unclear. The term "acute mental confusion" [ 1 ] is often used interchangeably with delirium [ 2 ] in the International Statistical Classification of Diseases and Related Health Problems and the Medical Subject Headings publications to describe the pathology .
When the steroid treatment ended after a year, the patent's confusion and disorganized appearance stopped immediately. Within several weeks, testing showed strong improvement in almost all cognitive functions. His doctors were surprised at the improvement, since the results were inconsistent with a diagnosis of dementia or Alzheimer's.