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A myxoid liposarcoma is a malignant adipose tissue neoplasm [1] of myxoid appearance histologically.. Myxoid liposarcomas are the second-most common type of liposarcoma, representing 30–40% of all liposarcomas in the limbs, occurring most commonly in the legs, particularly the thigh, followed by the buttocks, retroperitoneum, trunk, ankle, proximal limb girdle, head and neck, and wrist.
Since ultrasonography is usually unable to distinguish a liposarcoma from a benign lipoma, MRI is the initial imaging of choice to provide evidence relative to making this distinction. [67] In myxoid liposarcoma, it shows low signal intensity mass with high signal intensity foci on T1-weighted MRI images.
Liposarcoma is found in 1% of lipomas and is more likely to occur in lesions of the lower extremities, shoulders, and retroperitoneal areas. Other risk factors for liposarcoma include large size (>5 cm), associated with calcification, rapid growth, and/or invasion into nearby structures or through fascia into muscle tissue. [39]
Liposarcoma treatment usually consists of surgical resection, with chemotherapy considered depending on the aggressiveness of the sarcoma. Radiotherapy may also be used before or after surgical excision for liposarcoma. [21] Pediatric rhabdomyosarcoma is usually treated with chemotherapy, surgery, and sometimes radiotherapy. [22]
Liposarcoma: Arms, legs, trunk Muscle (striated) Rhabdomyosarcoma: Arms, legs Muscle (smooth) Leiomyosarcoma: Uterus, digestive tract Blood vessels Angiosarcoma: Arms, legs, trunk, radiated tissues Kaposi sarcoma: Legs, trunk Lymph vessels Angiosarcoma: Arms Peripheral nerves Malignant peripheral nerve sheath tumor / Neurofibrosarcoma: Arms ...
English: Histopathology of liposarcoma, H&E stain, with the main features: [1] - Spindle cells with enlarged, hyperchromatic nuclei. - Apparently univacuolated adipocytes (may look normal). - Lipoblasts (multivacuolated), but neither necessary nor sufficient for diagnosis. This case was likely a myxoid liposarcoma as per immunohistochemistry ...
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A synovial sarcoma (also known as malignant synovioma [1]) is a rare form of cancer which occurs primarily in the extremities of the arms or legs, often in proximity to joint capsules and tendon sheaths. [2]