Ads
related to: canavan's disease progression timeline graph templatemonday.com has been visited by 100K+ users in the past month
- 200+ Templates
Hit the Ground Running
With Ready-Made Templates
- Pricing & Plans
Simple, Fair Pricing that Scales
with Your Workforce.
- 200+ Templates
nulab.com has been visited by 10K+ users in the past month
simplenursing.com has been visited by 10K+ users in the past month
Search results
Results From The WOW.Com Content Network
Symptoms of the most common (and most serious) form of Canavan disease typically appear in early infancy usually between the first three to six months of age. [4] Canavan disease then progresses rapidly from that stage, with typical cases involving intellectual disability, loss of previously acquired motor skills, feeding difficulties, abnormal muscle tone (i.e., initial floppiness ...
The first case of spongy degeneration of the CNS was reported in 1928 by Globus and Strauss, [42] who designated the case as Schilder's disease, a term for diffuse myelinoclastic sclerosis. [43] [44] [45] In 1931, Canavan reported a case where the megalencephaly of brain degeneration is different from that caused by a tumour. [46]
Canavan disease is a less-studied type of leukodystrophy that, like MLD and Krabbe disease, is also inherited in an autosomal recessive pattern. It is due to a mutation in the ASPA gene that encodes aspartoacylase , an enzyme needed to metabolize N-acetyl-L-aspartate (NAA).
All participants demonstrated progress on administered developmental/motor assessments as measured by the GMFM-88, HINE-2, CDC milestones, or the Canavan Disease Rating Scale BBP-812 continues to be generally well-tolerated, with a safety profile consistent with other systemically administered AAV9 gene therapies
If the template has a separate documentation page (usually called "Template:template name/doc"), add [[Category:Graphical timeline templates]] to the <includeonly> section at the bottom of that page.
“Canavan disease is an extremely rare and rapidly progressive neurodegenerative disease that prevents most children from meeting basic developmental milestones, such as crawling, walking, speaking, and even holding their heads up. It is a terminal diagnosis with no approved treatment to date.
Ad
related to: canavan's disease progression timeline graph templatemonday.com has been visited by 100K+ users in the past month