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The gestational sac is spherical in shape, and is usually located in the upper part (fundus) of the uterus.By approximately nine weeks of gestational age, due to folding of the trilaminar germ disc, the amniotic sac expands and occupy the majority of the volume of the gestational sac, eventually reducing the extraembryonic coelom (the gestational sac or the chorionic cavity) to a thin layer ...
[2] [7] A pregnancy is anembryonic if a transvaginal ultrasound reveals a sac with a mean gestational sac diameter (MGD) greater than 25 mm and no yolk sac, or an MGD >25 mm with no embryo. [9] A transabdominal ultrasound can be used to diagnose anembryonic pregnancy if a gestational sac can be identified, but is empty. [3]
The yolk sac is the first element seen within the gestational sac during pregnancy, [1] usually at three days gestation. The yolk sac is situated on the front part of the embryo; it is lined by extra-embryonic endoderm, [3] outside of which is a layer of extra-embryonic mesenchyme, derived from the epiblast.
The amniotic sac, also called the bag of waters [1] [2] or the membranes, [3] is the sac in which the embryo and later fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth .
The yolk sac is a membranous sac attached to an embryo, formed by cells of the hypoblast layer of the bilaminar embryonic disc. This is alternatively called the umbilical vesicle . In humans, the yolk sac is important in early embryonic blood supply.
Gestational sac 15-35mm, embryo smaller than 25mm (corresponding to between 7 and 9+0 weeks of gestational age): Medication is recommended. Surgery or expectant management may be considered. Gestational sac smaller than 15-20mm, corresponding to a gestational age of less than 7 weeks: Expectant management or medication is preferable.
Mean gestational sac diameter of 16–24 mm and no embryo. [110] [111] Absence of embryo with heartbeat at least 2 weeks after an ultrasound scan that showed a gestational sac without a yolk sac. Absence of embryo with heartbeat 7–13 days after an ultrasound scan that showed a gestational sac without a yolk sac. [110] [111]
Gestational sac size, location, and number; Identification of the embryo and/or yolk sac; Measurement of fetal length (known as the crown-rump length) Fetal number, including number of amnionic sacs and chorionic sacs for multiple gestations; Embryonic/fetal cardiac activity; Assessment of embryonic/fetal anatomy appropriate for the first trimester