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Cats with chronic feline lower urinary tract disease caused by struvite uroliths are sometimes treated with a lifelong diet of prescription wet food as these special diets acidify urine which dissolve struvite. However ordinary wet food with high moisture content and rich in animal protein can be just as effective in many cases as it keeps the ...
However struvite crystals tend to form in concentrated, alkaline urine when the pH is greater than 6.5. Therefore, stress (which can cause alkalinity [ 27 ] ) or supersaturated urine (caused by lack of hydration or by stagnant urine collecting in the bladder due to urinary retention) both encourage crystal formation.
More than 90 percent of dogs with struvite stones have an associated urease-producing bacterial infection in the urinary tract, but in cats struvite stones usually form in sterile urine. [7] The appearance of the stones vary from large solitary stones to multiple smaller stones. They can assume the shape of the bladder or urethra. Struvite crystals
The protein cauxin, a protein excreted in large amounts in cat urine that acts to produce a feline pheromone, has recently been found to cause nucleation of struvite crystals in a model system containing the ions necessary to form struvite. This may explain some of the excess struvite production in domestic cats. [14]
Cauxin protein from feline urine was reported in 2008 to act as a nucleator for struvite crystals, in an in vivo system containing magnesium, ammonium, and phosphate ions. [8] Thus, this protein may act as one cause for feline urinary stones.
Crystalluria refers to crystals found in the urine when performing a urine test. Crystalluria is considered often as a benign condition and as one of the side effects of sulfonamides and penicillins. The main reason for the identification of urinary crystals is to detect the presence of the relatively few abnormal types that may represent a ...
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