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Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas. [1]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
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A diagnosis of postinflammatory hyperpigmentation is established based upon its clinical presentation coupled with a recent history of inflammation over the same area. Diagnostic tests are not required, but can rule out some other conditions, such as Addison's disease or systemic lupus erythematosus. Wood’s lamp evaluation can be used in the ...
According to Dr. Wechsler, melasma typically manifests as dark brown, patch-like spots and can appear anywhere on the face—cheeks, forehead, and nose being most common (though it can strike near ...
Whether caused by hyperpigmentation, acne, sun damage or aging, dark spots are one of the most common — and most annoying — skin concerns. Trust me, I know. I’ve been struggling with post ...