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Dermatomyositis (DM) is a long-term inflammatory autoimmune disorder which affects the skin and the muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity.
Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
dermatomyositis: Pathologic Basis of Disease (8th Ed), Robbins & Cotran: Scaling, erythematous eruption or dusky red patches over the knuckles, elbows and knees Gowers' sign [3] William Richard Gowers: neurology: muscular dystrophy: Graham Steell murmur: Graham Steell: cardiology: mitral stenosis
overlapping symptoms (such as muscle weakness, pain, elevated CK); that delaying treatment for an inflammatory myopathy, in order to exclude potential non-inflammatory myopathies, may cause irreversible damage (although administering immunosuppressants and glucocorticosteroids to non-inflammatory myopathies may also cause damage);
The three main types of idiopathic myositis (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. [4] Other autoimmune diseases, such as systemic lupus erythematosus , can also cause myositis-like symptoms.
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis .
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