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  2. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    The parenteral route is any route that is not enteral (par-+ enteral). Parenteral administration can be performed by injection, that is, using a needle (usually a hypodermic needle) and a syringe, [16] or by the insertion of an indwelling catheter. Locations of application of parenteral administration include: Central nervous system:

  3. Developmental toxicity - Wikipedia

    en.wikipedia.org/wiki/Developmental_toxicity

    Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis, normal growth, differentiation, development or behavior.

  4. Childhood dementia - Wikipedia

    en.wikipedia.org/wiki/Childhood_dementia

    Childhood dementia is an umbrella group of rare, mostly untreatable neurodegenerative disorders that show symptoms before the age of 18. These conditions cause progressive deterioration of the brain and the loss of previously acquired skills such as talking, walking, and playing.

  5. Neurotoxin - Wikipedia

    en.wikipedia.org/wiki/Neurotoxin

    Local pathology of neurotoxin exposure often includes neuron excitotoxicity or apoptosis [14] but can also include glial cell damage. [15] Macroscopic manifestations of neurotoxin exposure can include widespread central nervous system damage such as intellectual disability, [5] persistent memory impairments, [16] epilepsy, and dementia. [17]

  6. Toxic encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_encephalopathy

    Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...

  7. Dementia - Wikipedia

    en.wikipedia.org/wiki/Dementia

    This is an accepted version of this page This is the latest accepted revision, reviewed on 3 February 2025. Long-term brain disorders causing impaired memory, thinking and behavior This article is about the cognitive disorder. For other uses, see Dementia (disambiguation). "Senile" and "Demented" redirect here. For other uses, see Senile (disambiguation) and Demented (disambiguation). Medical ...

  8. Drug-induced amnesia - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_amnesia

    Drug-induced amnesia is amnesia caused by drugs. Amnesia may be therapeutic for medical treatment or for medical procedures, or it may be a side-effect of a drug, such as alcohol, or certain medications for psychiatric disorders, such as benzodiazepines. [1] It is seen also with slow acting parenteral general anaesthetics. [citation needed]

  9. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...